VOLUME 37, ISSUE 2
Joshua B. Cohen, M.D.
Assistant Professor, Baylor College of Medicine
The Texas Heart Institute
Baylor St. Luke’s Medical Center
Houston, TX
Cerebral Oximetry: Is it the Standard of Care or Not?
I heard a recent presentation at a resident conference about complications during cardiac surgery, including large stroke. One of the discussion points that came up was the use of cerebral oximetry during cardiac surgery to potentially detect and/or prevent neurologic injury and stroke. Should it be used routinely? Does it actually have the ability to detect ongoing or acute cerebral ischemia during surgery? Some of my colleagues and I continued to discuss it over the next few days. The next week, I took care of a patient for routine aortocoronary bypass, and cerebral oximetry came up during surgery when the surgeon requested that we use it for all of his cases. He then commented to his resident that cerebral oximetry “is the standard of care for heart surgery.” I wasn’t so sure, and have been thinking about it since: Is cerebral oximetry the standard of care or not?
What a complicated question! The first task in deciding is to define the “standard of care.” We use this very important phrase, but I would guess that many are not able to accurately define what it means. In medical malpractice law, the “standard of care” is the minimally competent care that physicians must provide to meet the quality of care that is required by law.1 Of course, that statement requires further clarification: What is “minimally competent care?” We can ask ourselves: What would a similarly qualified and reasonable medical professional do under similar circumstances? If someone of equal training, experience, and qualifications found themselves in a similar situation, what would they do? This isn’t perfect, but it gets us closer to understanding what it means to be using the “standard of care.”
There are endless discussions one could have regarding various aspects of anesthetic practice that might be considered to be the “standard of care.” For example, consider pulse oximetry. Pulse oximetry was developed in the 1970’s and has been accepted as a “standard of care” monitor since 1989 when it was included in the American Society of Anesthesiologists’ (ASA) “Standards for Basic Anesthetic Monitoring.”2 I can confidently assume that 100% of anesthesiologists today would agree without question that pulse oximetry is considered to be the standard of care for any anesthetic that is conducted today. But can the same be said of cerebral oximetry?
Cerebral oximetry is commonly used during cardiac surgery that utilizes cardiopulmonary bypass and aims to monitor cerebral oxygenation and detect cerebral “desaturation” events. The goal of cerebral oximetry use is identifying and treating cerebral ischemia and, hopefully, preventing post-operative neurological complications. This goal sounds wonderful, but is cerebral oximetry effective and does it improve outcomes? These are the key questions and, until they can be answered, I think the jury is still out on cerebral oximetry’s inclusion in the “standard of care” club.
What do the experts and guidelines say? On my review, I discovered that existing guidelines are surprisingly quiet on the subject of cerebral oximetry. The ASA does not offer any guidelines or consensus statements that mention cerebral oximetry. The same goes for the Society of Cardiovascular Anesthesiologists and the Society for Neuroscience in Anesthesiology and Critical Care. In 2020 the American Society of Enhanced Recovery and the Perioperative Quality Initiative published a joint consensus statement on the role of cerebral oximetry in perioperative outcomes.3 In their statement, there was an agreement that “there is insufficient evidence to recommend using intraoperative cerebral oximetry to reduce mortality or organ-specific morbidity after cardiac surgery” and that “there is insufficient evidence to recommend using intraoperative cerebral oximetry to improve outcomes after noncardiac surgery.
What do the surgeons think? The Society of Thoracic Surgeons (STS) does not have any clinical practice guidelines that discuss cerebral oximetry, but a recent joint consensus statement in 2024 from the Enhanced Recovery After Surgery (ERAS) Cardiac Society, ERAS International Society, and the STS on “Perioperative Care in Cardiac Surgery” addressed “Central Nervous System Monitoring,” which included both depth of anesthesia monitoring and cerebral oximetry. 4 They assert that, “although the monitoring method can provide benefit, it is unclear which interventions are optimal for prevention of neurologic morbidity” and that “additional study is necessary to identify strategies to prevent and mitigate injury.” They characterized the quality of the evidence they considered to be “moderate.”
There are review articles, studies, and meta-analyses that attempt to sort this all out, but it seems like the one thing they can all agree on is that there is insufficient evidence to really know for sure.
All of this is not to say that cerebral oximetry is a bad or useless monitor. The information that this monitor provides is quite remarkable and I have personally seen real time changes in cerebral oximetry values that were directly related to a clinical situation, proving that the monitor does provide very real information that can be useful in specific scenarios. But circling back to our original question: Is it the standard of care or not?
Clearly, the medical literature and guidelines on a topic such as cerebral oximetry can be diverse, with differing conclusions that can often be in conflict with one another, and reasonable anesthesiologists of similar training and experience might be able to equally justify the decision to use or not to use cerebral oximetry based on those conclusions. In their letter to the editor of the Journal of Cardiothoracic and Vascular Anesthesia, Marymont et al. addressed this very issue, opining that “both options are allowable with the legal definition of the standard of care.”5 The question of cerebral oximetry’s utility during cardiac surgery (as with countless other diagnostic and treatment options in medicine) is not black and white, and so it follows that its inclusion as part of the “standard of care” isn’t either. Perhaps one day, with more robust evidence and experience it will be, but I am convinced that, at the present time, it is not.
References:
- https://www.fsmb.org/siteassets/advocacy/policies/standards-of-care-policy.pdf
- https://www.asahq.org/standards-and-practice-parameters/standards-for-basic-anesthetic-monitoring
- Thiele RH, Shaw AD, Bartels K, Brown CH 4th, Grocott H, Heringlake M, Gan TJ, Miller TE, McEvoy MD; Perioperative Quality Initiative (POQI) 6 Workgroup. American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on the Role of Neuromonitoring in Perioperative Outcomes: Cerebral Near-Infrared Spectroscopy. Anesth Analg. 2020 Nov;131(5):1444-1455. doi: 10.1213/ ANE.0000000000005081. PMID: 33079868.
- Grant MC, Crisafi C, Alvarez A, Arora RC, Brindle ME, Chatterjee S, Ender J, Fletcher N, Gregory AJ, Gunaydin S, Jahangiri M, Ljungqvist O, Lobdell KW, Morton V, Reddy VS, Salenger R, Sander M, Zarbock A, Engelman DT. Perioperative Care in Cardiac Surgery: A Joint Consensus Statement by the Enhanced Recovery After Surgery (ERAS) Cardiac Society, ERAS International Society, and The Society of Thoracic Surgeons (STS). Ann Thorac Surg. 2024 Apr;117(4):669-689. doi: 10.1016/j.athoracsur.2023.12.006. Epub 2024 Jan 28. Erratum in: Ann Thorac Surg. 2024 Aug;118(2):524-525. doi: 10.1016/j.athoracsur.2024.06.006. PMID: 38284956.
- Marymont JH, Shear TD, Novak TE, Roberts JD, Greenberg SB. Is Cerebral Oximetry Monitoring a Standard-of-Care During Cardiac Surgery? J Cardiothorac Vasc Anesth. 2021;35(10):3145-3146. doi:10.1053/j.jvca.2021.02.061
